"The Twilight Saga: New Moon" opened Friday and immediately ripped through a box office record.

Security forces in Afghanistan have killed or captured more than 30 high-level militants, including many accused of participating in roadside bomb attacks, military officials said.

Health care reform backers won a key victory Saturday night as the Senate voted to move ahead with a floor debate on a sweeping $848 billion bill.

More than 80 Michael Jackson collectibles -- including the late pop star's famous rhinestone-studded glove from a 1983 performance -- were auctioned off Saturday, reaping a total $2 million.

Students occupying an administration building at the University of California, Santa Cruz, for the past three nights expect police to soon begin forcibly removing them, a student spokesman said.

Israeli fighter jets attacked what the country said were "terrorist sites" in Gaza in retribution for an earlier attack, the military said Sunday.

A prosecutor says American Amanda Knox and her former boyfriend should get life sentences if they are convicted in the death of a British student, a lawyer for the victim's family told CNN on Saturday.

Every Friday afternoon, the backpacks are placed carefully on the floors of the hallways in the elementary schools of Moberly, Missouri.

William Least Heat-Moon, best-selling author of "Blue Highways," "River-Horse," and most recently "Roads to Quoz," shared his insights on the American road with CNN. What follows is an edited transcript of that conversation.

Iran plans to launch a large aerial military exercise Sunday to prepare for any possible attack, state media said.